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Preparing for knee replacement surgery is the part of this process you control completely, and it changes outcomes more than most people expect. After more than twenty years and over 700 joint replacements a year, I can usually tell in the first week of recovery who did the work ahead of time. The operation takes about ninety minutes. The preparation takes about six weeks, and it is the better investment.
What are the 6 essential steps to prepare for knee replacement surgery?
The six steps are: optimize your medical health, sort out your medications, finish dental work, build quadriceps strength, set up your home, and line up your help. All six happen before you arrive at the surgery center.
- Optimize your health. Blood sugar, blood pressure, heart and lung clearance, weight, and smoking.
- Review medications. Blood thinners, anti-inflammatories, supplements, immune-modulating drugs.
- Finish dental work. Cleanings, extractions, and any active infection.
- Build strength. Quadriceps first, upper body second.
- Prepare your home. Clear paths, reachable items, safer bathroom.
- Arrange help. A driver, someone to stay with you, meals, pet or child care.
How soon before knee replacement surgery should preparation start?
Start 4 to 6 weeks before your date. That window is long enough to finish medical clearance, adjust medications safely, complete dental work, and build real strength in your leg. Muscle does not change in a weekend.
If your surgery is sooner, do not panic. Two focused weeks still helps. But if you have the choice, take the longer runway.
Knee Replacement Surgery Preparation Timeline: What To Do And When
| When | What to do | Why it matters |
|---|---|---|
| 6 weeks before | Complete medical clearance with your primary care physician and any specialists. Begin quadriceps work and low-impact conditioning. | Clearance often uncovers something that takes weeks to correct, and muscle needs time to respond to training. |
| 4 weeks before | Finish dental work. Line up your driver, the person staying with you the first few days, and pet or child care. | Bacteria from dental infection can settle on a new joint, and helpers need notice to clear their schedules. |
| 2 weeks before | Set up the home: clear floors, widen walking paths, position a firm chair, add bathroom safety items, stock meals. | Doing this while you are still mobile is far easier than doing it in the first week after surgery. |
| 1 week before | Attend your pre-operative appointment. Confirm exactly which medications and supplements to hold, and when. | Blood thinners, NSAIDs, and several supplements raise bleeding risk and need a planned hold window. |
| Night before | Follow the fasting instructions exactly. Wash with the antimicrobial soap provided. Do not shave the leg. | Eating or drinking outside the window cancels cases, and shaving creates small cuts that raise infection risk. |
| Morning of | Take only the medications you were told to take, with a sip of water. Bring photo ID, insurance card, and your medication list. | A clean handoff at check-in keeps your case on schedule and prevents last-minute medication questions. |
Timelines vary by patient and by surgical team. Always follow the written instructions your own surgeon provides.
How do you get medically ready for knee replacement surgery?
Getting medically ready means bringing the conditions you already have into the best control possible, because each one affects infection risk and healing. Your primary care physician and any specialists you see are part of that.
- Diabetes. Blood sugar control has a direct, measurable effect on infection risk and wound healing. For a patient with diabetes, it is the highest-yield step available, and entirely within their control.
- Heart and lung health. Known cardiac or pulmonary conditions require formal clearance, often from a cardiologist, before we schedule.
- Smoking. Nicotine narrows small blood vessels, which slows healing and raises infection risk. Stopping before surgery and staying stopped through recovery gives the knee the best conditions to heal.
- Body weight. Higher body weight raises wound complications, infection risk, and anesthesia demands. I have replaced knees successfully across a wide range of body weights; that conversation is never about closing a door, only about seeing the full picture.
- Bone health. Osteoporosis, meaning thinned bone, changes how an implant anchors. It is not a disqualifier, but tell your surgeon early.
Patients who arrive optimized do better than patients who do not. That pattern has held for twenty years in my practice.
Which medications need to stop before knee replacement surgery?
Blood thinners, most over-the-counter anti-inflammatories, and several common supplements are usually stopped before knee replacement surgery, but the timing is individual and must come from your surgical team. Never stop a prescription on your own.
- Anticoagulants (blood thinners) such as warfarin, clopidogrel, apixaban, and rivaroxaban. The prescribing physician sets the hold window.
- NSAIDs (nonsteroidal anti-inflammatory drugs) including ibuprofen, naproxen, and aspirin, which affect clotting. Many teams stop these a week out.
- Supplements such as fish oil, vitamin E, ginkgo, ginseng, and turmeric, which can increase bleeding.
- Immune-modulating drugs for rheumatoid arthritis and psoriasis, often held around the surgical date.
Bring a written list of everything you take to every pre-operative visit, including anything bought without a prescription. Dose and frequency, not just the name. That one page prevents more problems than anything else patients hand me.
Why does dental work need to be finished before surgery?
Bacteria from an infected tooth or inflamed gum can enter the bloodstream and settle on a new implant, and a joint infection is far harder to treat than a cavity. So dental work comes first: cleanings, fillings, extractions, and periodontal treatment, done and healed before your date.
Most teams then ask patients to wait several weeks after surgery before routine dental care resumes. Keep your dentist informed that you have a joint replacement.

What exercises should you do before knee replacement surgery?
Do quadriceps work, low-impact conditioning, and upper-body strengthening. Quad sets, straight leg raises, seated knee extensions, cycling, walking, and swimming all count. Fifteen to twenty minutes most days beats an hour once a week.
A worry I hear often is that exercising a bad knee damages it further. It does not. Pain in an arthritic knee is information, not injury, and low-impact activity does not wear it out faster.
I do not usually send patients to formal physical therapy before surgery. What I ask is simpler: find what your body will allow, and do more of it.
You can say no to anything. You just have to say yes to something.
Why the quadriceps matters more than any other muscle
The quadriceps, the large muscle group on the front of the thigh, drives every early milestone: straightening the leg, standing from a chair, climbing a stair, walking without a limp. A patient who arrives strong has a very different first two weeks than one who arrives deconditioned.
Surgery replaces worn cartilage and bone. It cannot replace muscle. That part is yours, and the time to build it is before surgery. Upper-body work matters too, because stronger arms make a walker or cane much easier to use.
How do you prepare your home for knee replacement recovery?
Clear the floor, bring daily items up to arm level, make the bathroom safer, and create one comfortable place to sit and elevate the leg. Fewer obstacles, not a hospital room.
Unlike hip replacement, knee replacement comes with no formal movement restrictions. You can take stairs from day one and sleep in your own bed. Home setup simply reduces friction so your energy goes into rehabilitation instead of logistics.
- Remove throw rugs and secure loose cords along the wall.
- Widen walking paths to about three feet so a walker fits.
- Set up a firm chair with arms; low, soft couches are hard to rise from.
- Keep a charger, water, ice packs, and medications within reach of that chair.
What equipment is actually worth getting?
A walker, a raised toilet seat, a shower chair, a grabber, and a few extra pillows cover most patients. Everything else is optional. Borrow before you buy: plenty of families around Franklin, Nashville, and Columbia already have a walker in a closet. Try moving through your own doorways with it before your date.
What should you arrange for surgery day and the first week?
Arrange a driver, someone to stay with you the first few days, coverage for pets and children, and help with errands. Do this a month out, not the night before. You will not drive for roughly one to three weeks, until you are off narcotic pain medication and can react safely.
Ask specifically. People want to help and rarely know what to offer. Give them a task: a meal Tuesday, the lawn for three weeks, a ride Thursday.
What should you pack for the day of surgery?
Pack light: photo identification, insurance card, your written medication list, an advance directive if you have one, loose clothing, slip-on shoes, phone and charger, and glasses or a contact case. Leave jewelry and valuables at home.
Follow your fasting instructions exactly. Eating or drinking outside those windows is one of the few things that cancels a case on the morning of surgery.
What happens at the pre-operative appointment?
Your pre-operative visit confirms medical clearance, finalizes the medication plan, reviews anesthesia, and gives you written instructions for the night before and morning of surgery. Testing often includes bloodwork, an EKG, and sometimes a chest X-ray. Bring your written questions, and bring whoever is helping you.
You will likely be asked to wash with an antimicrobial soap the night before and the morning of surgery, and not to shave the leg yourself. If you develop a fever, a rash, or any break in the skin on that leg beforehand, call the office. It is far better to move a date than to treat an infection in a new joint.
Preparing for knee replacement surgery in Franklin and Middle Tennessee
Patients come to our Franklin office from Nashville, Brentwood, Spring Hill, Columbia, Murfreesboro, and Nolensville, and the first question is almost always some version of what should I be doing right now. The answer is the six steps above, started early.
In my practice I use the subvastus approach, which works underneath the quadriceps tendon rather than cutting through it. It is designed to protect the muscle you spent six weeks building.
Still deciding? Start with total knee replacement and our nonsurgical joint pain treatment options. If your date is set, the patient resources page and free joint replacement guide go deeper.
Ready to talk it through? Schedule a consultation with Dr. Calendine, or call Bone and Joint Institute of Tennessee at (615) 791-2630. Our office is at 3000 Edward Curd Lane, Franklin, TN 37067.
References
- Evans JT, Walker RW, Evans JP, Blom AW, Sayers A, Whitehouse MR. How long does a knee replacement last? A systematic review and meta-analysis of case series and national registry reports with more than 15 years of follow-up. The Lancet. 2019;393(10172):655-663. PubMed
- Moyer R, Ikert K, Long K, Marsh J. The value of preoperative exercise and education for patients undergoing total hip and knee arthroplasty: a systematic review and meta-analysis. JBJS Reviews. 2017;5(12):e2. PubMed
- Shohat N, Muhsen K, Gilat R, Rondon AJ, Chen AF, Parvizi J. Inadequate glycemic control is associated with increased surgical site infection in total joint arthroplasty: a systematic review and meta-analysis. Journal of Arthroplasty. 2018;33(7):2312-2321.e3. PubMed
- Duchman KR, Gao Y, Pugely AJ, Martin CT, Noiseux NO, Callaghan JJ. The effect of smoking on short-term complications following total hip and knee arthroplasty. Journal of Bone and Joint Surgery (American). 2015;97(13):1049-1058. PubMed
- McDonald S, Page MJ, Beringer K, Wasiak J, Sprowson A. Preoperative education for hip or knee replacement. Cochrane Database of Systematic Reviews. 2014;(5):CD003526. PubMed
Medical disclaimer: This article is for general education and does not replace personalized medical advice, diagnosis, or treatment. Every patient’s situation differs. Always consult your own orthopaedic surgeon and healthcare team before making decisions about surgery or changing any medication.




