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A high-angle, extreme close-up shot focusing on a child's hands clutching their knee. The child is wearing light-colored pants. This visually represents juvenile arthritis and joint pain in children.

Juvenile Arthritis Diseases

Juvenile Arthritis (JA), an umbrella term for various inflammatory and rheumatic diseases in children under 16, affects over 300,000 kids and teens in the United States annually. Often under-diagnosed due to symptoms that can mimic normal growing pains, it is crucial to understand that JA goes beyond simple joint stiffness. With significant genetic components, JA can also severely impact internal organs and vision. Understanding the facts about early diagnosis and treatment is the first step toward improving a child’s quality of life.

Juvenile arthritis (JA) is an umbrella term that describes a spectrum of inflammatory and rheumatic diseases that develop in children under the age of 16. Juvenile arthritis affects more than 300,000 US children and teens each year.

Most types of JA are autoimmune or autoinflammatory diseases, meaning the body produces inflammatory chemicals that attack healthy cells and tissue. Common symptoms and consequences of  JA include joint inflammation, swelling, pain and tenderness.

Surprising Facts About Juvenile Arthritis

1. Juvenile arthritis is often under-diagnosed.

Many children with juvenile arthritis suffer from joint pain and stiffness, loss of motion in joints, rash, fever and weight loss, but presenting symptoms in kids can be atypical. Parents and healthcare professionals who are not familiar with JA may mistake symptoms for normal growing pains or other disorders.

2. Juvenile arthritis usually has a genetic component.

Studies have confirmed that siblings and first cousins of children with juvenile arthritis have an increased risk of also developing the disease.

3. Juvenile arthritis can affect internal organs and systems.

10% -25% of children with the most common forms of JA often develop inflammation of the eyes (uveitis) that can lead to visual impairment if not detected and treated early. In systemic-onset juvenile arthritis (less common form of the disease), inflammation can damage the lining of the heart, lungs, liver and blood cells.

4. Exercise is always an important part of the treatment plan.

Physical activity and therapy helps strengthen muscles, improves joint range, and slow or limit joint damage. With advances in therapy over the last 30 years, many JA patients live symptom-free (although this may require medical treatment).

5. The prognosis for JA patients is improving.

Improved care, treatment options and diagnostic tools mean JA patients have more options and overall better quality of life.

Additional Information from National Arthritis FoundationJuvenile Arthritis (JA)

Video: What is Arthritis?, Cory Calendine, MD, Orthopedic Surgeon

https://www.youtube.com/embed/QHa3C4Y13nc
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FREQUENTLY ASKED QUESTIONS

Common Questions From Readers

What is the Most Common Type of Juvenile Arthritis?
The most prevalent form is Juvenile Idiopathic Arthritis (JIA), a group of conditions causing joint inflammation in children under 16. It is an autoimmune disease, meaning the child’s immune system attacks healthy tissue in the joints. There are several subtypes of JIA, each with distinct features.
In some cases, yes. Growing pains typically affect the muscles of the legs at night, but they do not cause joint swelling or redness. However, juvenile arthritis (JA) is frequently misdiagnosed because its symptoms, like joint pain and stiffness, can be subtle or atypical in young children. If joint symptoms are persistent, or a child is limping or has unexplained fever and fatigue, a medical evaluation is critical to rule out JA.
Yes, it can. Uveitis, a form of eye inflammation, is a serious complication that affects a significant number of children with JA (between 10% and 25% for the most common forms). Because it is often asymptomatic in its early stages, regular eye exams by an ophthalmologist are a vital part of JA management to prevent visual impairm
Absolutely. Physical activity is a fundamental part of a juvenile arthritis treatment plan. Gentle, appropriate exercise and physical therapy help to strengthen the muscles supporting the joints, improve and maintain a range of motion, and slow or even limit joint damage. Activity is vital to helping children manage pain and avoid long-term mobility issues.
There is no definitive cure for JA, but early diagnosis and advanced therapies mean many children can live symptom-free, though they may require ongoing medical treatment. Research indicates a genetic component, as siblings and first cousins of affected children are at an increased risk, suggesting that some children may be genetically predisposed to developing the condition.
Dr. Cory Calendine, MD, board-certified orthopedic surgeon specializing in hip and knee replacement at the Bone and Joint Institute of Tennessee in Franklin, TN, shown in a gray suit with glasses and a blue tie during a professional portrait session.

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About Cory Calendine, MD

Dr. Cory Calendine is a board-certified, fellowship-trained orthopedic surgeon specializing in hip and knee replacement at the Bone and Joint Institute of Tennessee in Franklin, TN. He performs more than 700 hip and knee replacement procedures annually and serves as a consultant to Stryker for the Mako® robotic platform.

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